Special Reference: Immunopathogenesis, Prevalence and Management of Celiac Disease

Special Reference: Immunopathogenesis, Prevalence and Management of Celiac Disease

  • Stene LC, Honeyman MC, Hoffenberg EJ, et al. Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal study. Am J Gastroenterol 2006;101:2333-2340.
  • Ivarsson A. The Swedish epidemic of coeliac disease explored using an epidemiological approach — some lessons to be learnt. Best Pract Res Clin Gastroenterol 2005;19:425-440.
  • West J, Logan RF, Hill PG, et al. Seroprevalence, correlates, and characteristics of undetected coeliac disease in England. Gut 2003;52:960-965.
  • Mäki M, Mustalahti K, Kokkonen J, et al. Prevalence of celiac disease among children in Finland. N Engl J Med 2003;348:2517-2524.
  • Tatar G, Elsurer R, Simsek H, et al. Screening of tissue transglutaminase antibody in healthy blood donors for celiac disease screening in the Turkish population. Dig Dis Sci 2004;49:1479-1484.
  • Fasano A, Berti I, Gerarduzzi T, et al. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Arch Intern Med 2003;163:286-292.
  • Bingley PJ, Williams AJ, Norcross AJ, et al. Undiagnosed coeliac disease at age seven: population based prospective birth cohort study. BMJ 2004;328:322-323.
  • Gale J, Simmonds PD, Mead GM, Sweetenham JW, Wright DH. Enteropathy-type intestinal T-cell lymphoma: clinical features and treatment of 31 patients in a single center. J Clin Oncol 2000;18:795-803.
  • Rongey C, Micallef I, Smyrk T, Murray J. Successful treatment of enteropathy-associated T cell lymphoma with autologous stem cell transplant. Dig Dis Sci 2006;51:1082-1086.
  • Trier JS. Celiac sprue. N Engl J Med 1991;325:1709-1719.
  • Cellier C, Patey N, Mauvieux L, et al. Abnormal intestinal intraepithelial lymphocytes in refractory sprue. Gastroenterology 1998;114:471-481.
  • Verkarre V, Asnafi V, Lecomte T, et al. Refractory coeliac sprue is a diffuse gastrointestinal disease. Gut 2003;52:205-211.
  • Carbonnel F, Grollet-Bioul L, Brouet JC, et al. Are complicated forms of celiac disease cryptic T-cell lymphomas? Blood 1998;92:3879-3886.
  • Daum S, Weiss D, Hummel M, et al. Frequency of clonal intraepithelial T lymphocyte proliferations in enteropathy-type intestinal T cell lymphoma, coeliac disease, and refractory sprue. Gut 2001;49:804-812.
  • Patey-Mariaud De Serre N, Cellier C, Jabri B, et al. Distinction between coeliac disease and refractory sprue: a simple immunohistochemical method. Histopathology 2000;37:70-77.
  • Cellier C, Cuillerier E, Patey-Mariaud de Serre N, et al. Push enteroscopy in celiac sprue and refractory sprue. Gastrointest Endosc 1999;50:613-617.
  • Mauriño E, Niveloni S, Cherñavsky A, et al. Azathioprine in refractory sprue: results from a prospective, open-label study. Am J Gastroenterol 2002;97:2595-2602.
  • Wahab PJ, Crusius JB, Meijer JW, Uil JJ, Mulder CJ. Cyclosporin in the treatment of adults with refractory coeliac disease — an open pilot study. Aliment Pharmacol Ther 2000;14:767-774.
  • Goerres MS, Meijer JW, Wahab PJ, et al. Azathioprine and prednisone combination therapy in refractory coeliac disease. Aliment Pharmacol Ther 2003;18:487-494.
  • Gillett HR, Arnott ID, McIntyre M, et al. Successful infliximab treatment for steroid-refractory celiac disease: a case report. Gastroenterology 2002;122:800-805.
  • Vivas S, Ruiz de Morales JM, Ramos F, Suarez-Vilela D. Alemtuzumab for refractory celiac disease in a patient at risk for enteropathy-associated T-cell lymphoma. N Engl J Med 2006;354:2514-2515. [Erratum, N Engl J Med 2006;355:856.
  • Al-Toma A, Goerres MS, Meijer JW, et al. Cladribine therapy in refractory celiac disease with aberrant T cells. Clin Gastroenterol Hepatol 2006;4:1322-1327.
  • Al-toma A, Visser OJ, van Roessel HM, et al. Autologous hematopoietic stem cell transplantation in refractory celiac disease with aberrant T cells. Blood 2007;109:2243-2249.
  • Collins JR, Isselbacher KJ. Treatment of adult celiac disease (nontropical sprue). N Engl J Med 1964;271:1153-1156.
  • Trier JS, Falchuk ZM, Carey MC, Schreiber DS. Celiac sprue and refractory sprue. Gastroenterology 1978;75:307-316.
  • Green PH, Jabri B. Coeliac disease. Lancet 2003;362:383-391.
  • Shan L, Molberg Ø, Parrot I, et al. Structural basis for gluten intolerance in celiac sprue. Science 2002;297:2275-2279.
  • Sollid LM. Coeliac disease: dissecting a complex inflammatory disorder. Nat Rev Immunol 2002;2:647-655.
  • Nilsen EM, Jahnsen FL, Lundin KE, et al. Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease. Gastroenterology 1998;115:551-563.
  • Molberg O, McAdam SN, Körner R, et al. Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease. Nat Med 1998;4:713-717. [Erratum, Nat Med 1998;4:974.]
  • Mohamed BM, Feighery C, Kelly J, et al. Increased protein expression of matrix metalloproteinases -1, -3, and -9 and TIMP-1 in patients with gluten-sensitive enteropathy. Dig Dis Sci 2006;51:1862-1868.
  • Mention JJ, Ben Ahmed M, Bègue B, et al. Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease. Gastroenterology 2003;125:730-745. [CrossRef][ISI
  • Meresse B, Chen Z, Ciszewski C, et al. Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease. Immunity 2004;21:357-366.
  • Hüe S, Mention JJ, Monteiro RC, et al. A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease. Immunity 2004;21:367-377.
  • Bevan S, Popat S, Braegger CP, et al. Contribution of the MHC region to the familial risk of coeliac disease. J Med Genet 1999;36:687-690.
  • Sollid LM, Lie BA. Celiac disease genetics: current concepts and practical applications. Clin Gastroenterol Hepatol 2005;3:843-851.
  • Greco L, Romino R, Coto I, et al. The first large population based twin study of coeliac disease. Gut 2002;50:624-628.
  • Bardella MT, Molteni N, Prampolini L, et al. Need for follow up in coeliac disease. Arch Dis Child 1994;70:211-213.
  • Cellier C, Delabesse E, Helmer C, et al. Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma. Lancet 2000;356:203-208.
  • Rampertab SD, Forde KA, Green PH. Small bowel neoplasia in coeliac disease. Gut 2003;52:1211-1214.
  • West J, Logan RF, Smith CJ, Hubbard RB, Card TR. Malignancy and mortality in people with coeliac disease: population based cohort study. BMJ 2004;329:716-719.
  • Askling J, Linet M, Gridley G, Halstensen TS, Ekström K, Ekbom A. Cancer incidence in a population-based cohort of individuals hospitalized with celiac disease or dermatitis herpetiformis. Gastroenterology 2002;123:1428-1435.
  • Smedby KE, Akerman M, Hildebrand H, Glimelius B, Ekbom A, Askling J. Malignant lymphomas in coeliac disease: evidence of increased risks for lymphoma types other than enteropathy-type T cell lymphoma. Gut 2005;54:54-59.
  • Green PH, Fleischauer AT, Bhagat G, Goyal R, Jabri B, Neugut AI. Risk of malignancy in patients with celiac disease. Am J Med 2003;115:191-195.
  • Green PH, Rampertab SD. Small bowel carcinoma and coeliac disease. Gut 2004;53:774-774.
  • Culliford A, Daly J, Diamond B, Rubin M, Green PH. The value of wireless capsule endoscopy in patients with complicated celiac disease. Gastrointest Endosc 2005;62:55-61.
  • Howdle PD, Jalal PK, Holmes GK, Houlston RS. Primary small-bowel malignancy in the UK and its association with coeliac disease. QJM 2003;96:345-353.
  • Bagdi E, Diss TC, Munson P, Isaacson PG. Mucosal intra-epithelial lymphocytes in enteropathy-associated T-cell lymphoma, ulcerative jejunitis, and refractory celiac disease constitute a neoplastic population. Blood 1999;94:260-264.
  • Persson LA, Ivarsson A, Hernell O. Breast-feeding protects against celiac disease in childhood — epidemiological evidence. Adv Exp Med Biol 2002;503:115-123.
  • Ivarsson A, Hernell O, Stenlund H, Persson LA. Breast-feeding protects against celiac disease. Am J Clin Nutr 2002;75:914-921. [Free Full Text]
  • Carlsson A, Agardh D, Borulf S, Grodzinsky E, Axelsson I, Ivarsson SA. Prevalence of celiac disease: before and after a national change in feeding recommendations. Scand J Gastroenterol 2006;41:553-558.
  • Norris JM, Barriga K, Hoffenberg EJ, et al. Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA 2005;293:2343-2351.
  • Shahbazkhani B, Malekzadeh R, Sotoudeh M, et al. High prevalence of coeliac disease in apparently healthy Iranian blood donors. Eur J Gastroenterol Hepatol 2003;15:475-478.
  • Sood A, Midha V, Sood N, Malhotra V. Adult celiac disease in northern India. Indian J Gastroenterol 2003;22:124-126.
  • Gomez JC, Selvaggio GS, Viola M, et al. Prevalence of celiac disease in Argentina: screening of an adult population in the La Plata area. Am J Gastroenterol 2001;96:2700-2704.
  • Catassi C, Rätsch IM, Gandolfi L, et al. Why is coeliac disease endemic in the people of the Sahara? Lancet 1999;354:647-648.
  • Murray JA, Van Dyke C, Plevak MF, Dierkhising RA, Zinsmeister AR, Melton LJ III. Trends in the identification and clinical features of celiac disease in a North American community, 1950-2001. Clin Gastroenterol Hepatol 2003;1:19-27.
  • D’Amico MA, Holmes J, Stavropoulos SN, et al. Presentation of pediatric celiac disease in the United States: prominent effect of breastfeeding. Clin Pediatr (Phila) 2005;44:249-258.
  • Green PHR, Stavropoulos SN, Panagi SG, et al. Characteristics of adult celiac disease in the USA: results of a national survey. Am J Gastroenterol 2001;96:126-131.
  • Rampertab SD, Pooran N, Brar P, Singh P, Green PH. Trends in the presentation of celiac disease. Am J Med 2006;119(4):355.e9-355.e14.
  • Green PH, Shane E, Rotterdam H, Forde KA, Grossbard L. Significance of unsuspected celiac disease detected at endoscopy. Gastrointest Endosc 2000;51:60-65.
  • Sategna-Guidetti C, Pulitanó R, Grosso S, et al. Serum IgA antiendomysium antibody titers as a marker of intestinal involvement and diet compliance in adult celiac sprue. J Clin Gastroenterol. Sep 1993;17(2):123-7.
  • Smedby KE, Akerman M, Hildebrand H, et al. Malignant lymphomas in coeliac disease: evidence of increased risks for lymphoma types other than enteropathy-type T cell lymphoma. Gut. Jan 2005;54(1):54-9.
  • Thompson T. National Institutes of Health consensus statement on celiac disease. J Am Diet Assoc. Feb 2005;105(2):194-5.
  • Trier JS. Diagnosis of celiac sprue. Gastroenterology. Jul 1998;115(1):211-6.
  • Tursi A, Brandimarte G, Giorgetti GM. Prevalence of antitissue transglutaminase antibodies in different degrees of intestinal damage in celiac disease. J Clin Gastroenterol. Mar 2003;36(3):219-21.
  • Yachha SK, Misra S, Malik AK, Nagi B, Mehta S. Spectrum of malabsorption syndrome in north Indian children. Indian J Gastroenterol. Oct 1993;12(4):120-5.
  • uandalini S, Setty M. Celiac disease. Curr Opin Gastroenterol. Nov 2008;24(6):707-12.
  • Tang F, Chen Z, Ciszewski C, et al. Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15. J Exp Med. Feb 23 2009
  • Marsh MN, Hinde J. Inflammatory component of celiac sprue mucosa. I. Mast cells, basophils, and eosinophils. Gastroenterology. Jul 1985;89(1):92-101.
  • Catassi C, Kryszak D, Louis-Jacques O, et al. Detection of Celiac disease in primary care: a multicenter case-finding study in North America. Am J Gastroenterol. Jul 2007;102(7):1454-60.
  • Lohi S, Mustalahti K, Kaukinen K, Laurila K, Collin P, Rissanen H, et al. Increasing prevalence of coeliac disease over time. Aliment Pharmacol Ther. Nov 1 2007;26(9):1217-25.
  • Kondrashova A, Mustalahti K, Kaukinen K, Viskari H, Volodicheva V, Haapala AM, et al. Lower economic status and inferior hygienic environment may protect against celiac disease. Ann Med. 2008;40(3):223-31.
  • Catassi C, Cobellis G. Coeliac disease epidemiology is alive and kicking, especially in the developing world. Dig Liver Dis. Oct 2007;39(10):908-10.
  • Silano M, Volta U, Vincenzi AD, Dessì M, Vincenzi MD. Effect of a gluten-free diet on the risk of enteropathy-associated T-cell lymphoma in celiac disease. Dig Dis Sci. Apr 2008;53(4):972-6.
  • Metzger MH, Heier M, Mäki M, Bravi E, Schneider A, Löwel H, et al. Mortality excess in individuals with elevated IgA anti-transglutaminase antibodies: the KORA/MONICA Augsburg cohort study 1989-1998. Eur J Epidemiol. 2006;21(5):359-65.
  • Guandalini S, ed. Celiac Disease. In. Textbook of Pediatric Gastroenterology and Nutrition. London: Taylor & Francis;. 2004: 435-50.
  • Pope R, Sheiner E. Celiac disease during pregnancy: to screen or not to screen?. Arch Gynecol Obstet. Jan 2009;279(1):1-3.
  • Akobeng AK, Ramanan AV, Buchan I, Heller RF. Effect of breast feeding on risk of coeliac disease: a systematic review and meta-analysis of observational studies. Arch Dis Child. Jan 2006;91(1):39-43.
  • Olsson C, Hernell O, Hornell A, Lonnberg G, Ivarsson A. Difference in celiac disease risk between Swedish birth cohorts suggests an opportunity for primary prevention. Pediatrics. Sep 2008;122(3):528-34.
  • Troncone R, Auricchio S. Rotavirus and celiac disease: clues to the pathogenesis and perspectives on prevention. J Pediatr Gastroenterol Nutr. May 2007;44(5):527-8.
  • Bonamico M, Mariani P, Thanasi E, et al. Patchy villous atrophy of the duodenum in childhood celiac disease. J Pediatr Gastroenterol Nutr. Feb 2004;38(2):204-7.
  • Rostom A, Murray JA, Kagnoff MF. American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology. Dec 2006;131(6):1981-2002.
  • Hill ID, Dirks MH, Liptak GS, et al. Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. Jan 2005;40(1):1-19.
  • Walker-Smith JA, Guandalini S, Schmitz J, Shmerling DH, Visakorpi JK. Revised criteria for diagnosis of coeliac disease. Report of Working Group of European Society of Paediatric Gastroenterology and Nutrition. Arch Dis Child. 1990;65:909-911.
  • Kurppa K, Collin P, Viljamaa M, et al. Diagnosing mild enteropathy celiac disease: a randomized, controlled clinical study. Gastroenterology. Mar 2009;136(3):816-23.
  • Akobeng AK, Thomas AG. Systematic review: tolerable amount of gluten for people with coeliac disease. Aliment Pharmacol Ther. Jun 1 2008;27(11):1044-52.
  • Leffler DA, Dennis M, Edwards GJ, et al. A Simple Validated Gluten-Free Diet Adherence Survey for Adults With Celiac Disease. Clin Gastroenterol Hepatol. Jan 11 2009
  • University of Chicago Celiac Disease Center. Available at www.celiacdisease.net.
  • Isselbacher KJ, Braunwald E, Wilson JD. Harrison’s Principles of Internal Medicine. 13th ed. New York, NY: McGraw Hill; 1994:1398-400.
  • McCance KL, Huether SE. Pathophysiology: The Biologic Basis for Disease in Adults and Children. St Louis, MO: Mosby; 1990:1277-80.
  • Saltzman JR, Russell RM. The aging gut. Nutritional issues. Gastroenterol Clin North Am. Jun 1998;27(2):309-24.
  • USP. United States Pharmacopeial Convention: Drug Information (USP DI) for the Health Care Professional. 16th ed. Rockville, MD: United States Pharmacopeial Convention; 1996:978-95.
  • Askling J, Linet M, Gridley G, et al. Cancer incidence in a population-based cohort of individuals hospitalized with celiac disease or dermatitis herpetiformis. Gastroenterology. Nov 2002;123(5):1428-35.
  • Catassi C, Rätsch IM, Fabiani E, Rossini M, Bordicchia F, Candela F. Coeliac disease in the year 2000: exploring the iceberg. Lancet. Jan 22 1994;343(8891):200-3.
  • Collin P, Kaukinen K, Vogelsang H, et al. Antiendomysial and antihuman recombinant tissue transglutaminase antibodies in the diagnosis of coeliac disease: a biopsy-proven European multicentre study. Eur J Gastroenterol Hepatol. Jan 2005;17(1):85-91.
  • Dieterich W, Ehnis T, Bauer M, et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med. Jul 1997;3(7):797-801.
  • Farrell RJ, Kelly CP. Celiac sprue. N Engl J Med. Jan 17 2002;346(3):180-8.
  • Fasano A, Berti I, Gerarduzzi T, et al. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Arch Intern Med. Feb 10 2003;163(3):286-92.
  • Ferguson A, Arranz E, O’Mahony S. Clinical and pathological spectrum of coeliac disease–active, silent, latent, potential. Gut. Feb 1993;34(2):150-1.
  • Godkin A, Jewell D. The pathogenesis of celiac disease. Gastroenterology. Jul 1998;115(1):206-10.
  • Greco L, Romino R, Coto I, et al. The first large population based twin study of coeliac disease. Gut. May 2002;50(5):624-8.
  • Green PH, Cellier C. Celiac disease. N Engl J Med. Oct 25 2007;357(17):1731-43.
  • Green PH, Jabri B. Coeliac disease. Lancet. Aug 2 2003;362(9381):383-91.
  • James MW, Scott BB. Coeliac disease: the cause of the various associated disorders?. Eur J Gastroenterol Hepatol. Sep 2001;13(9):1119-21.
  • Johnson TC, Diamond B, Memeo L, et al. Relationship of HLA-DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts. Clin Gastroenterol Hepatol. Oct 2004;2(10):888-94.
  • Kagnoff MF. Celiac disease: pathogenesis of a model immunogenetic disease. J Clin Invest. Jan 2007;117(1):41-9.
  • Mention JJ, Ben Ahmed M, Begue B, et al. Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease. Gastroenterology. Sep 2003;125(3):730-45.
  • Murray JA, Van Dyke C, Plevak MF, et al. Trends in the identification and clinical features of celiac disease in a North American community, 1950-2001. Clin Gastroenterol Hepatol. Jan 2003;1(1):19-27.
  • Murray JA, Van Dyke C, Plevak MF, et al. Trends in the identification and clinical features of celiac disease in a North American community, 1950-2001. Clin Gastroenterol Hepatol. Jan 2003;1(1):19-27.
  • Rostami K, Malekzadeh R, Shahbazkhani B, et al. Coeliac disease in Middle Eastern countries: a challenge for the evolutionary history of this complex disorder?. Dig Liver Dis. Oct 2004;36(10):694-7.
  • Rostom A, Murray JA, Kagnoff MF. American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology. Dec 2006;131(6):1981-2002.
  • Salmi TT, Collin P, Korponay-Szabo IR, et al. Endomysial antibody-negative coeliac disease: clinical characteristics and intestinal autoantibody deposits. Gut. Dec 2006;55(12):1746-53.
  • Sanders DS, Hurlstone DP, McAlindon ME, et al. Antibody negative coeliac disease presenting in elderly people–an easily missed diagnosis. BMJ. Apr 2 2005;330(7494):775-6.
  • Green PH, Jabri B: Coeliac disease. Lancet 2003, 362:383-391. ** This is an excellent, brief review of current concepts in CD and their clinical relevance.
  • Sanders DS, Patel D, Stephenson TJ, et al.: A primary care cross-sectional study of undiagnosed adult coeliac disease. Eur J Gastroenterol Hepatol 2003, 15:407-413.
  • Shahbazkhani B, Forootan M, Merat S, et al.: Coeliac disease presenting with symptoms of irritable bowel syndrome. Aliment Pharmacol Ther 2003, 18:231-235.
  • Zipser RD, Patel S, Yahya KZ, et al.: Presentations of adult celiac disease in a nationwide patient support group. Dig Dis Sci 2003, 48:761-764.
  • Cranney A, Zarkadas M, Graham ID, et al.: The Canadian celiac health survey-the Ottawa chapter pilot. Available: http.www.biomedcentral.com/1471-230x/3/8.
  • Hogberg L, Falth-Magnusson K, Grodzinsky E, et al.: Familial prevalence of coeliac disease: a twenty-year follow-up study. Scand J Gastroenterol 2003, 38:61-65. * This is a long-term follow-up of a previous study cohort. It showed, reassuringly, no new cases of CD diagnosed in first-degree relatives of patients with CD over a period of 20 to 25 years (if a previously normal histology was documented).
  • Book L, Zone JJ, Neuhausen SL: Prevalence of celiac disease among relatives of sib pairs with celiac disease in U.S. families. Am J Gastroenterol 2003, 98:377-381.
  • Abdulkarim AS, Murray JA: Review article: the diagnosis of coeliac disease. Aliment Pharmacol Ther 2003, 17:987-995. ** This is a good summary of the clinical findings and associations of CD in adults and children. However, the number of CD patients is relatively small.
  • Carroccio A, Vitale G, Di Prima L, et al.: Comparison of anti-transglutaminase ELISAs and an anti-endomysial antibody assay in the diagnosis of celiac disease: a prospective study. Clin Chem 2002, 48:1546-1550. * This is a prospective series of serologic testing in CD and non-CD patients.
  • Sinclair D, Pearce CB, Saas MS, et al.: A comparative study of tissue transglutaminase antibodies and endomysium antibody immunofluorescence in routine clinical laboratory practice. Ann Clin Biochem 2003, 40:411-416. * This is a useful comparison of different commercially available kits available for anti-h-tTG and anti-gp-tTG.
  • Blackwell PJ, Hill PG, Holmes GK: Autoantibodies to human tissue transglutaminase: superior predictors of coeliac disease. Scand J Gastroenterol 2002, 37:1282-1285. * This is another comparison of different commercially available anti-tTG kits, with some kits being tested varying from those tested by Sinclair et al.[10*]
  • Tesei N, Sugai E, Vazquez H, et al.: Antibodies to human recombinant tissue transglutaminase may detect coeliac disease patients undiagnosed by endomysial antibodies. Aliment Pharmacol Ther 2003, 17:1415-1423. ** This is an excellent, large study comparing the different serologic tests now available to laboratories for diagnosing CD. It puts into context the potential role of tTG in serologic testing.
  • Vivas S, Ruiz de Morales JM, Martinez J, et al.: Human recombinant anti-transglutaminase antibody testing is useful in the diagnosis of silent coeliac disease in a selected group of at-risk patients. Eur J Gastroenterol Hepatol 2003, 15:479-483.
  • Agardh D, Borulf S, Lernmark A, et al.: Tissue transglutaminase immunoglobulin isotypes in children with untreated and treated celiac disease. J Pediatr Gastroenterol Nutr 2003, 36:77-82. * This study outlines the difficulties in serologic testing of those younger than 2 years of age.
  • Vahedi K, Mascart F, Mary JY, et al.: Reliability of antitransglutaminase antibodies as predictors of gluten-free diet compliance in adult celiac disease. Am J Gastroenterol 2003, 98:1079-1087. * This study confirms that tTG antibodies cannot be used as a measure of GFD compliance.
  • Stulik J, Hernychova L, Porkertova S, et al.: Identification of new celiac disease autoantigens using proteomic analysis. Proteomics 2003, 3:951-956. * This is an interesting approach to identifying CD autoantigens, although the conclusions are a little speculative.
  • Sjolund K, Ekman R: Plasma motilin in untreated celiac disease. Peptides 2003, 24:483-486.
  • Merendino RA, Di Pasquale G, Sturniolo GC, et al.: Relationship between IL-18 and sICAM-1 serum levels in patients affected by coeliac disease: preliminary considerations. Immunol Lett 2003, 85:257-260.
  • Laurin P, Falth-Magnusson K, Sundqvist T: Increase in nitric oxide urinary products during gluten challenge in children with coeliac disease. Scand J Gastroenterol 2003, 38:55-60.
  • Tursi A, Brandimarte G, Giorgetti GM: Sorbitol H2-breath test versus anti-endomysium antibodies to assess histological recovery after gluten-free diet in coeliac disease. Dig Liver Dis 2002, 34:846-850. * This is an interesting paper on how a perhaps underused noninvasive test is possibly better at monitoring histologic recovery than current serologic means.
  • Laghi A, Paolantonio P, Catalano C, et al.: MR imaging of the small bowel using polyethylene glycol solution as an oral contrast agent in adults and children with celiac disease: preliminary observations. AJR Am J Roentgenol 2003, 180:191-194.
  • Magalotti D, Volta U, Bonfiglioli A, et al.: planchnic haemodynamics in patients with coeliac disease: effects of a gluten-free diet. Dig Liver Dis 2003, 35:262-268.
  • Karell K, Louka AS, Moodie SJ, et al.: HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European genetics cluster on celiac disease. Hum Immunol 2003, 64:469-477.
  • Louka AS, Moodie SJ, Karell K, et al.: A collaborative European search for non-DQA1*05-DQB1*02 celiac disease loci on HLA-DR3 haplotypes: analysis of transmission from homozygous parents. Hum Immunol 2003, 64:350-358.
  • Bolognesi E, Karell K, Percopo S, et al.: Additional factor in some HLA DR3/DQ2 haplotypes confers a fourfold increased genetic risk of celiac disease. Tissue Antigens 2003, 61:308-316. ** This pan-European study sheds light on why the B8-DR3 extended haplotype may confer an increased risk of CD. It links with other recent work about the potential role of MICA alleles.
  • Mustalahti K, Holopainen P, Karell K, et al.: Genetic dissection between silent and clinically diagnosed symptomatic forms of coeliac disease in multiplex families. Dig Liver Dis 2002, 34:842-845. * This is a brief, readable paper on how HLA DR-DQ haplotypes do not seem to influence the severity of CD.
  • Vogelsang H, Panzer S, Mayr WR, et al.: Distribution of HLA class I alleles differs in celiac disease patients according to age of onset. Dig Dis Sci 2003, 48:611-614.
  • Cheng S, Baisch J, Krco S, et al.: Expression and function of HLA-DQ8 (DQA1*0301/DQB1*0302) genes in transgenic mice. Eur J Immunogenet 1996, 23:15-20.
  • Black KE, Murray JA, David CS: HLA-DQ determines the response to exogenous wheat proteins: a model of gluten sensitivity in transgenic knockout mice. J Immunol 2002, 169:5595-5600. ** This is an elegant paper describing the development of a potential new animal model for CD. The study demonstrates how the transgenic animal seems to respond immunologically to gliadin as a patient with CD would.
  • Mazzarella G, Maglio M, Paparo F, et al.: An immunodominant DQ8 restricted gliadin peptide activates small intestinal immune response in in vitro cultured mucosa from HLA-DQ8 positive but not HLA-DQ8 negative coeliac patients. Gut 2003, 52:57-62.
  • Arentz-Hansen H, McAdam SN, Molberg O, et al.: Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues. Gastroenterology 2002, 123:803-809. ** This paper identifies new potential DQ2-restricted T-cell epitopes in α- and γ- gliadinsggr;-gliadins. It contains a good discussion of why these proline-rich domains may be exerting their effect.
  • Gianfrani C, Troncone R, Mugione P, et al.: Celiac disease association with CD8+ T cell responses: identification of a novel gliadin-derived HLA-A2-restricted epitope. J Immunol 2003, 170:2719-2726. * This study links an α-gliadin epitope with CD8+ T-cell responses.
  • Giovannini C, Matarrese P, Scazzocchio B, et al.: Wheat gliadin induces apoptosis of intestinal cells via an autocrine mechanism involving Fas-Fas ligand pathway. FEBS Lett 2003, 540:117-124. * This study explores the mechanisms of how gliadin may induce intestinal cell apoptosis in CD. An interesting protective effect is described of a small peptide derived from durum wheat.
  • Clemente MG, De Virgiliis S, Kang JS, et al.: Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function. Gut 2003, 52:218-223. * This report contains a description of a newly discovered mammalian protein that effects tight junctions in intestinal mucosa.
  • Maiuri L, Ciacci C, Ricciardelli I, et al.: Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease. Lancet 2003, 362:30-37. ** This is a brief and elegant paper on how a gliadin fragment is able to activate the innate immune system. This has implications regarding how gliadin may augment the T-cell response to its own dominant epitopes.
  • Nieuwenhuizen WF, Pieters RH, Knippels LM, et al.: Is Candida albicans a trigger in the onset of coeliac disease? Lancet 2003, 361:2152-2154. ** This is only a hypothesis, but the paper is well structured. It explains in a convincing and clear manner the potential link between C. albicans and CD.
  • Rueda B, Pascual M, Lopez-Nevot MA, et al.: A new allele within the transmembrane region of the human MICA gene with seven GCT repeats. Tissue Antigens 2002, 60:526-528. * This report puts the recent work linking MICA genes and CD into some context.
  • Rueda B, Pascual M, Lopez-Nevot MA, et al.: Association of MICA-A5.1 allele with susceptibility to celiac disease in a family study. Am J Gastroenterol 2003, 98:359-362. * As well as finding a new association between an MICA allele and susceptibility to CD (independent of the DQ2 haplotype), the authors clarify (but only in the discussion, and not experimentally) the role that MICA may play.
  • Ruoppolo M, Orru S, D’Amato A, et al.: Analysis of transglutaminase protein substrates by functional proteomics. Protein Sci 2003, 12:1290-1297.
  • Orru S, Caputo I, D’Amato A, et al.: Proteomics identification of Acyl-acceptor and Acyl-donor substrates for transglutaminase in a human intestinal epithelial cell line: implications for coeliac disease. J Biol Chem 2003 (in press).
  • Korponay-Szabo IR, Laurila K, Szondy Z, et al.: Missing endomysial and reticulin binding of coeliac antibodies in transglutaminase 2 knockout tissues. Gut 2003, 52:199-204.
  • Verkarre V, Romana SP, Cellier C, et al.: Recurrent partial trisomy 1q22-q44 in clonal intraepithelial lymphocytes in refractory celiac sprue. Gastroenterology 2003, 125:40-46. ** This interesting paper links the malignant potential of RCS with alterations of karyotype, similar to those seen in other malignancies. It may provide future information about the mechanisms behind lymphomatous transformation and possibly has the potential for being a prognostic indicator in RCS.
  • Verkarre V, Asnafi V, Lecomte T, et al.: Refractory coeliac sprue is a diffuse gastrointestinal disease. Gut 2003, 52:205-211.
  • Maurino E, Niveloni S, Chernavsky A, et al.: Azathioprine in refractory sprue: results from a prospective, open-label study. Am J Gastroenterol 2002, 97:2595-2602. * These exciting results show clinical remission in RCS. However, this was a small uncontrolled series of patients and one death is probably linked to azathioprine administration.
  • Sidney J, del Guercio MF, Southwood S, et al.: The HLA molecules DQA1*0501/B1*0201 and DQA1*0301/B1*0302 share an extensive overlap in peptide binding specificity. J Immunol 2002, 169:5098-5108. * This is an interesting paper that demonstrates how there may be a common antigen explaining the association seen between CD and type I diabetes.
  • Volta U, De Giorgio R, Petrolini N, et al.: Clinical findings and anti-neuronal antibodies in coeliac disease with neurological disorders. Scand J Gastroenterol 2002, 37:1276-1281.
  • Jiskra J, Limanova Z, Vanickova Z, et al.: IgA and IgG antigliadin, IgA anti-tissue transglutaminase and antiendomysial antibodies in patients with autoimmune thyroid diseases and their relationship to thyroidal replacement therapy. Physiol Res 2003, 52:79-88.
  • Howdle PD, Jalal PK, Holmes GK, et al.: Primary small-bowel malignancy in the UK and its association with coeliac disease. Q J Med 2003, 96:345-353. * This study confirms the increased risk of developing these relatively rare tumors in CD, but also clarifies the risks for patients in the United Kingdom.
  • Peters U, Askling J, Gridley G, et al.: Causes of death in patients with celiac disease in a population-based Swedish cohort. Arch Intern Med 2003, 163:1566-1572. * The long study period documented in this paper confirms CD patients have increased mortality rates overall, not just from small bowel malignancies, but also from other broadly autoimmune conditions.
  • Askling J, Linet M, Gridley G, et al.: Cancer incidence in a population-based cohort of individuals hospitalized with celiac disease or dermatitis herpetiformis. Gastroenterology 2002, 123:1428-1435. * This is a cohort similar to that of Peters et al.[49*]
  • Rampertab SD, Forde KA, Green PH: Small bowel neoplasia in coeliac disease. Gut 2003, 52:1211-1214. * This is a nice series detailing three cases of small bowel adenoma and one case (out of four) of small bowel adenocarcinoma in CD patients.
  • Valdes I, Garcia E, Llorente M, et al.: Innovative approach to low-level gluten determination in foods using a novel sandwich enzyme-linked immunosorbent assay protocol. Eur J Gastroenterol Hepatol 2003, 15:465-474. * The authors describe a novel sandwich R5-ELISA that in combination with a new gluten extraction procedure can detect very low levels of gliadins, hordeins, and secalins. They have tested it already against more than 4400 food samples.
  • Peraaho M, Kaukinen K, Paasikivi K, et al.: Wheat-starch-based gluten-free products in the treatment of newly detected coeliac disease: prospective and randomized study. Aliment Pharmacol Ther 2003, 17:587-594.
  • Janatuinen EK, Pikkarainen PH, Kemppainen TA, et al.: A comparison of diets with and without oats in adults with celiac disease. N Engl J Med 1995, 333:1033-1037.
  • Thompson T: Oats and the gluten-free diet. J Am Diet Assoc 2003, 103:376-379. ** This is a brief and highly readable summary of the recent literature on the role of oats in a GFD.
  • Storsrud S, Olsson M, Arvidsson LR, et al.: Adult coeliac patients do tolerate large amounts of oats. Eur J Clin Nutr 2003, 57:163-169.
  • Kilmartin C, Lynch S, Abuzakouk M, et al.: Avenin fails to induce a Th1 response in coeliac tissue following in vitro culture. Gut 2003, 52:47-52. * This is a good quality piece of laboratory work that confirms recent clinical work that oats are safe for consumption by CD patients.
  • Senger S, Luongo D, Maurano F, et al.: Intranasal administration of a recombinant alpha-gliadin down-regulates the immune response to wheat gliadin in DQ8 transgenic mice. Immunol Lett 2003, 88:127-134. * This study demonstrates how the immunogenic response to gluten in transgenic mice can be modified by intranasal administration of recombinant α-gliadin.
  • Tursi A, Brandimarte G: The symptomatic and histologic response to a gluten-free diet in patients with borderline enteropathy. J Clin Gastroenterol 2003, 36:13-17.
  • Tursi A, Brandimarte G, Giorgetti G: High prevalence of small intestinal bacterial overgrowth in celiac patients with persistence of gastrointestinal symptoms after gluten withdrawal. Am J Gastroenterol 2003, 98:839-843. * This report is a good reminder of potential coexisting gastrointestinal pathology that often exists in CD patients with continuing symptoms despite a GFD.
  • Green PH. The many faces of celiac disease: clinical presentation of celiac disease in the adult population. Gastroenterology 2005;128:Suppl 1:S74-S78.
  • Sanders DS, Carter MJ, Hurlstone DP, et al. Association of adult coeliac disease with irritable bowel syndrome: a case-control study in patients fulfilling ROME II criteria referred to secondary care. Lancet 2001;358:1504-1508.
  • Dickey W, Kearney N. Overweight in celiac disease: prevalence, clinical characteristics, and effect of a gluten-free diet. Am J Gastroenterol 2006;101:2356-2359.
  • Dickey W, McConnell JB. How many hospital visits does it take before celiac sprue is diagnosed? J Clin Gastroenterol 1996;23:21-23.
  • Ciacci C, Cavallaro R, Romano R, et al. Increased risk of surgery in undiagnosed celiac disease. Dig Dis Sci 2001;46:2206-2208.
  • Shamaly H, Hartman C, Pollack S, et al. Tissue transglutaminase antibodies are a useful serological marker for the diagnosis of celiac disease in patients with Down syndrome. J Pediatr Gastroenterol Nutr 2007;44:583-586.
  • Bettendorf M, Doerr HG, Hauffa BP, et al. Prevalence of autoantibodies associated with thyroid and celiac disease in Ullrich-Turner syndrome in relation to adult height after growth hormone treatment. J Pediatr Endocrinol Metab 2006;19:149-154.
  • Goh C, Banerjee K. Prevalence of coeliac disease in children and adolescents with type 1 diabetes mellitus in a clinic based population. Postgrad Med J 2007;83:132-136.
  • Ventura A, Magazzù G, Greco L. Duration of exposure to gluten and risk for autoimmune disorders in patients with celiac disease. Gastroenterology 1999;117:297-303.
  • Bai D, Brar P, Holleran S, Ramakrishnan R, Green PH. Effect of gender on the manifestations of celiac disease: evidence for greater malabsorption in men. Scand J Gastroenterol 2005;40:183-187.
  • Viljamaa M, Kaukinen K, Huhtala H, Kyronpalo S, Rasmussen M, Collin P. Coeliac disease, autoimmune diseases and gluten exposure. Scand J Gastroenterol 2005;40:437-443.
  • Catassi C, Kryszak D, Louis-Jacques O, et al. Detection of celiac disease in primary care: a multicenter case-finding study in North America. Am J Gastroenterol 2007;102:1454-1460.
  • Revised criteria for diagnosis of coeliac disease: report of Working Group of European Society of Paediatric Gastroenterology and Nutrition. Arch Dis Child 1990;65:909-911
  • Rostom A, Dubé C, Cranney A, et al. The diagnostic accuracy of serologic tests for celiac disease: a systematic review. Gastroenterology 2005;128:Suppl 1:S38-S46.
  • Sugai E, Vázquez H, Nachman F, et al. Accuracy of testing for antibodies to synthetic gliadin-related peptides in celiac disease. Clin Gastroenterol Hepatol 2006;4:1112-1117.
  • Dieterich W, Ehnis T, Bauer M, et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med 1997;3:797-801.
  • Sategna-Guidetti C, Pulitano R, Grosso S, Ferfoglia G. Serum IgA antiendomysium antibody titers as a marker of intestinal involvement and diet compliance in adult celiac sprue. J Clin Gastroenterol 1993;17:123-127.
  • Tursi A, Brandimarte G, Giorgetti GM. Prevalence of antitissue transglutaminase antibodies in different degrees of intestinal damage in celiac disease. J Clin Gastroenterol 2003;36:219-221.
  • Dickey W, Hughes D. Disappointing sensitivity of endoscopic markers for villous atrophy in a high-risk population: implications for celiac disease diagnosis during routine endoscopy. Am J Gastroenterol 2001;96:2126-2128.
  • Abrams JA, Diamond B, Rotterdam H, Green PHR. Seronegative celiac disease: increased prevalence with lesser degrees of villous atrophy. Dig Dis Sci 2004;49:546-550.
  • Wong RC, Wilson RJ, Steele RH, Radford-Smith G, Adelstein S. A comparison of 13 guinea pig and human anti-tissue transglutaminase antibody ELISA kits. J Clin Pathol 2002;55:488-494.
  • Rostom A, Murray JA, Kagnoff MF. American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology 2006;131:1981-2002.
  • Lenhardt A, Plebani A, Marchetti F, et al. Role of human-tissue transglutaminase IgG and anti-gliadin IgG antibodies in the diagnosis of coeliac disease in patients with selective immunoglobulin A deficiency. Dig Liver Dis 2004;36:730-734.
  • Dickey W, Hughes DF, McMillan SA. Reliance on serum endomysial antibody testing underestimates the true prevalence of coeliac disease by one fifth. Scand J Gastroenterol 2000;35:181-183.
  • Abrams JA, Brar P, Diamond B, Rotterdam H, Green PH. Utility in clinical practice of immunoglobulin A anti-tissue transglutaminase antibody for the diagnosis of celiac disease. Clin Gastroenterol Hepatol 2006;4:726-730.
  • Raivio T, Kaukinen K, Nemes E, et al. Self transglutaminase-based rapid coeliac disease antibody detection by a lateral flow method. Aliment Pharmacol Ther 2006;24:147-154.
  • Johnson TC, Diamond B, Memeo L, et al. Relationship of HLA-DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts. Clin Gastroenterol Hepatol 2004;2:888-894.
  • Kaukinen K, Partanen J, Mäki M, Collin P. HLA-DQ typing in the diagnosis of celiac disease. Am J Gastroenterol 2002;97:695-699.
  • Bonamico M, Mariani P, Thanasi E, et al. Patchy villous atrophy of the duodenum in childhood celiac disease. J Pediatr Gastroenterol Nutr 2004;38:204-207.
  • Ravelli A, Bolognini S, Gambarotti M, Villanacci V. Variability of histologic lesions in relation to biopsy site in gluten-sensitive enteropathy. Am J Gastroenterol 2005;100:177-185.
  • Lee SK, Green PH. Endoscopy in celiac disease. Curr Opin Gastroenterol 2005;21:589-594.
  • Oxentenko AS, Grisolano SW, Murray JA, Burgart LJ, Dierkhising RA, Alexander JA. The insensitivity of endoscopic markers in celiac disease. Am J Gastroenterol 2002;97:933-938.
  • Marsh MN. Gluten, major histocompatibility complex, and the small intestine: a molecular and immunobiologic approach to the spectrum of gluten sensitivity (`celiac sprue’). Gastroenterology 1992;102:330-354.
  • Memeo L, Jhang J, Hibshoosh H, Green PH, Rotterdam H, Bhagat G. Duodenal intraepithelial lymphocytosis with normal villous architecture: common occurrence in H. pylori gastritis. Mod Pathol 2005;18:1134-1144.
  • Peräaho M, Kaukinen K, Mustalahti K, et al. Effect of an oats-containing gluten-free diet on symptoms and quality of life in coeliac disease: a randomized study. Scand J Gastroenterol 2004;39:27-31.
  • Thompson T. Oats and the gluten-free diet. J Am Diet Assoc 2003;103:376-379.
  • Hallert C, Grant C, Grehn S, et al. Evidence of poor vitamin status in coeliac patients on a gluten-free diet for 10 years. Aliment Pharmacol Ther 2002;16:1333-1339.
  • Meyer D, Stavropolous S, Diamond B, Shane E, Green PH. Osteoporosis in a North American adult population with celiac disease. Am J Gastroenterol 2001;96:112-119.
  • Cellier C, Flobert C, Cormier C, Roux C, Schmitz J. Severe osteopenia in symptom-free adults with a childhood diagnosis of coeliac disease. Lancet 2000;355:806-806.
  • Lee SK, Lo W, Memeo L, Rotterdam H, Green PH. Duodenal histology in patients with celiac disease after treatment with a gluten-free diet. Gastrointest Endosc 2003;57:187-191.
  • Matysiak-Butnik T, Malamut G, Patey-Mariaud de Serre N, et al. Long-term follow-up of 61 celiac patients diagnosed in childhood: evolution toward latency is possible on a normal diet. Gut 2007;56:1379-1386.
  • Siegel M, Bethune MT, Gass J, et al. Rational design of combination enzyme therapy for celiac sprue. Chem Biol 2006;13:649-658.
  • Stepniak D, Spaenij-Dekking L, Mitea C, et al. Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease. Am J Physiol Gastrointest Liver Physiol 2006;291:G621-G629.
  • O’Mahony S, Howdle PD, Losowsky MS. Management of patients with non-responsive coeliac disease. Aliment Pharmacol Ther 1996;10:671-680.
  • Vahedi K, Mascart F, Mary JY, et al. Reliability of antitransglutaminase antibodies as predictors of gluten-free diet compliance in adult celiac disease. Am J Gastroenterol 2003;98:1079-1087.
  • Kumar PJ, Walker-Smith J, Milla P, Harris G, Colyer J, Halliday R. The teenage coeliac: follow up study of 102 patients. Arch Dis Child 1988;63:916-920.
  • Fabiani E, Taccari LM, Rätsch IM, Di Giuseppe S, Coppa GV, Catassi C. Compliance with gluten-free diet in adolescents with screening-detected celiac disease: a 5-year follow-up study. J Pediatr 2000;136:841-843.
  • Häuser W, Stallmach A, Caspary WF, Stein J (March 2007). “Predictors of reduced health-related quality of life in adults with coeliac disease”. Aliment. Pharmacol. Ther. 25 (5): 569–78.
  • Goddard CJ, Gillett HR (November 2006). “Complications of coeliac disease: are all patients at risk?“. Postgrad Med J 82 (973): 705–12. doi:10.1136/pgmj.2006.048876.
  • Häuser W, Gold J, Stein J, Caspary WF, Stallmach A (July 2006). “Health-related quality of life in adult coeliac disease in Germany: results of a national survey”. Eur J Gastroenterol Hepatol 18 (7): 747–54.
  • Siegel M, Bethune M, Gass J, Ehren J, Xia J, Johannsen A, Stuge T, Gray G, Lee P, Khosla C (2006). “Rational design of combination enzyme therapy for celiac sprue“. Chem Biol 13 (6): 649–58.
  • Poole J, Barriga K, Leung D, Hoffman M, Eisenbarth G, Rewers M, Norris J (2006). “Timing of initial exposure to cereal grains and the risk of wheat allergy“. Pediatrics 117 (6): 2175–82. doi:10.1542/peds.2005-1803. PMID 16740862. http://pediatrics.aappublications.org/cgi/content/full/117/6/2175.
  • Akobeng A, Ramanan A, Buchan I, Heller R (2006). “Effect of breast feeding on risk of coeliac disease: a systematic review and meta-analysis of observational studies“. Arch Dis Child 91 (1): 39–43. doi:10.1136/adc.2005.082016. PMID 16287899.
  • Treem W (2004). “Emerging concepts in celiac disease”. Curr Opin Pediatr 16 (5): 552–9.
  • Akobeng AK, Thomas AG (June 2008). “Systematic review: tolerable amount of gluten for people with coeliac disease”. Aliment. Pharmacol. Ther. 27 (11): 1044–52.
  • Questions and Answers on the Gluten-Free Labeling Proposed Rule”. US FDA. 2007-01-23. http://www.cfsan.fda.gov/~dms/glutqa.html.
  • Current Official Standards”. FAO/WHO.  Troncone R, Ivarsson A, Szajewska H, Mearin ML (June 2008). “Review article: future research on coeliac disease – a position report from the European multistakeholder platform on coeliac disease (CDEUSSA)“. Aliment. Pharmacol. Ther. 27 (11): 1030–43.
  • Lee AR, Ng DL, Zivin J, Green PH (October 2007). “Economic burden of a gluten-free diet”. J Hum Nutr Diet 20 (5): 423–30.
  • Fasano A, Not T, Wang W, Uzzau S, Berti I, Tommasini A, Goldblum S (2000). “Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease”. Lancet 355 (9214): 1518–9.
  • National Institute for Health and Clinical Excellence. Clinical guideline 53: Chronic fatigue syndrome/myalgic encephalomyelitis. London, 2007.
  • National Institute for Health and Clinical Excellence. Clinical guideline 61: Irritable bowel syndrome. London, 2008.
  • Corazza G, Valentini R, Andreani M, D’Anchino M, Leva M, Ginaldi L, De Feudis L, Quaglino D, Gasbarrini G (1995). “Subclinical coeliac disease is a frequent cause of iron-deficiency anaemia”. Scand J Gastroenterol 30 (2): 153–6.
  • Ransford R, Hayes M, Palmer M, Hall M (2002). “A controlled, prospective screening study of celiac disease presenting as iron deficiency anemia”. J Clin Gastroenterol 35 (3): 228–33.
  • Sjöberg K, Carlsson A (2004). “Screening for celiac disease can be justified in high-risk groups” (in Swedish). Lakartidningen 101 (48): 3912, 3915–6, 3918–9.
  • Catassi C, Rätsch I, Gandolfi L, Pratesi R, Fabiani E, El Asmar R, Frijia M, Bearzi I, Vizzoni L (1999). “Why is coeliac disease endemic in the people of the Sahara?”. Lancet 354 (9179): 647–8. doi:10.1016/S0140-6736(99)02609-4.
  • Zipser R, Farid M, Baisch D, Patel B, Patel D (2005). “Physician awareness of celiac disease: a need for further education“. J Gen Intern Med 20 (7): 644–6. doi:10.1111/j.1525-1497.2005.0107.x (inactive 2008-11-08). PMID 16050861.
  • Fasano A, Berti I, Gerarduzzi T, Not T, Colletti R, Drago S, Elitsur Y, Green P, Guandalini S, Hill I, Pietzak M, Ventura A, Thorpe M, Kryszak D, Fornaroli F, Wasserman S, Murray J, Horvath K (2003). “Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study“. Archives of Internal Medicine 163 (3): 286–92.
  • Barker JM, Liu E (2008). “Celiac disease: pathophysiology, clinical manifestations, and associated autoimmune conditions”. Adv Pediatr 55: 349–65.
  • Leeds JS, Hopper AD, Sanders DS (2008). “Coeliac disease”. Br Med Bull 88 (1): 157–70.
  • Jax Peter Lowell, The Gluten-Free Bible, p. 279.
  • Scott Adams (2 August 2002). “Bishops in Italy Approve a German-made Low Gluten Eucharistic Host”. Celiac.com.
  • Associated Press (8 December 2004). “Girl with digestive disease denied Communion“. MSNBC (Microsoft).
  • Ratzinger, Joseph (24 July 2003). Prot. 89/78-174 98. Congregation for the Doctrine of the Faith. Full text at: “The Use of Mustum and Low-Gluten Hosts at Mass”. BCL Newsletter. United States Conference of Catholic Bishops. November 2003. http://www.usccb.org/liturgy/innews/1103.shtml.
  • McNamara, Father Edward (2004-09-15). “Liturgy: Gluten-free Hosts”. Catholic Online. http://www.catholic.org/featured/headline.php?
  • Rabbi Avraham Juravel. “Gluten Intolerance, Celiac, Allergies And Pesach”. Orthodox Union.
  • Holmes, Geoff (2006). “History of coeliac disease”. Coeliac UK. http://www.coeliac.co.uk/coeliac_disease/68.asp.
  • Gee, SJ (1888). “On the coeliac affection“. St Bartholomew’s Hospital Report 24: 17–20.
  • Herter, CA (1908). On infantilism from chronic intestinal infection; characterized by the overgrowth and persistence of flora in the nursing period. New York: Macmillan & Co. as cited by WhoNamedIt
  • Ole Daniel Enersen. “Christian Archibald Herter”. Who Named It?. http://www.whonamedit.com/doctor.cfm/1490.html.
  • Haas SV (1924). “The value of the banana in the treatment of coeliac disease”. Am J Dis Child 24: 421–37.
  • van Berge-Henegouwen G, Mulder C (1993). “Pioneer in the gluten free diet: Willem-Karel Dicke 1905–1962, over 50 years of gluten free diet” (PDF). Gut 34 (11): 1473–5. doi:10.1136/gut.34.11.1473. PMID 8244125.
  • Dicke WK. Coeliakie: een onderzoek naar de nadelige invloed van sommige graansoorten op de lijder aan coeliakie [PhD thesis]. Utrecht, the Netherlands: University of Utrecht, 1950.
  • Anderson C, French J, Sammons H, Frazer A, Gerrard J, Smellie J (1952). “Coeliac disease; gastrointestinal studies and the effect of dietary wheat flour”. Lancet 1 (17): 836–42. doi:10.1016/S0140-6736(52)90795-2.
  • Paulley JW (1954). “Observation on the aetiology of idiopathic steatorrhoea; jejunal and lymph-node biopsies“. Br Med J 4900: 1318–21.
  • Shiner M (1956). “Duodenal biopsy”. Lancet 270 (6906): 17–9. doi:10.1016/S0140-6736(56)91854-2.
  • Macdonald W, Dobbins W, Rubin C (1965). “Studies of the familial nature of celiac sprue using biopsy of the small intestine”. N Engl J Med 272: 448–56.
  • van Heel D, West J (2006). “Recent advances in coeliac disease“. Gut 55 (7): 1037–46. doi:10.1136/gut.2005.075119.
  • Adams F, translator (1856). “On The Cœliac Affection”. The extant works of Aretaeus, The Cappadocian. London: Sydenham Society.
  • Ciclitira, P (2002). “Interim Guidelines for the Management of Patients with Coeliac Disease”. British Society of Gastroenterology.
  • Ferguson R, Basu M, Asquith P, Cooke W (1976). “Jejunal mucosal abnormalities in patients with recurrent aphthous ulceration“. Br Med J 1 (6000): 11–13.
  •  Spiegel BM, DeRosa VP, Gralnek IM, Wang V, Dulai GS (June 2004). “Testing for celiac sprue in irritable bowel syndrome with predominant diarrhea: a cost-effectiveness analysis”. Gastroenterology 126 (7): 1721–32.
  • American Gastroenterological Association medical position statement: Celiac Sprue“. Gastroenterology 120 (6): 1522–5. 2001. PMID 11313323.
  • Tursi A, Brandimarte G, Giorgetti G (2003). “High prevalence of small intestinal bacterial overgrowth in celiac patients with persistence of gastrointestinal symptoms after gluten withdrawal”. Am J Gastroenterol 98 (4): 839–43.
  • Crabbé P, Heremans J (1967). “Selective IgA deficiency with steatorrhea. A new syndrome”. Am J Med 42 (2): 319–26. doi:10.1016/0002-9343(67)90031-9.
  • Collin P, Mäki M, Keyriläinen O, Hällström O, Reunala T, Pasternack A (1992). “Selective IgA deficiency and coeliac disease”. Scand J Gastroenterol 27 (5): 367–71.
  • Marks J, Shuster S, Watson A (1966). “Small-bowel changes in dermatitis herpetiformis”. Lancet 2 (7476): 1280–2.
  • Eaton W, Mortensen P, Esben A, Byrne M, Mors O, Ewald H (2002). “Coeliac disease and schizophrenia: population based case control study with linkage of Danish national registers“. British Medical Journal 328: 438–9.
  • Pengiran Tengah D, Wills A, Holmes G (2002). “Neurological complications of coeliac disease“. Postgrad Med J 78 (921): 393–8.
  • Ferguson A, Hutton M, Maxwell J, Murray D (1970). “Adult coeliac disease in hyposplenic patients”. Lancet 1 (7639): 163–4.
  • Holmes G (2001). “Coeliac disease and Type 1 diabetes mellitus – the case for screening”. Diabet Med 18 (3): 169–77.
  • Collin P, Kaukinen K, Välimäki M, Salmi J (2002). “Endocrinological disorders and celiac disease“. Endocr Rev 23 (4): 464–83.
  • Kingham J, Parker D (1998). “The association between primary biliary cirrhosis and coeliac disease: a study of relative prevalences“. Gut 42 (1): 120–2
  • Matteoni C, Goldblum J, Wang N, Brzezinski A, Achkar E, Soffer E (2001). “Celiac disease is highly prevalent in lymphocytic colitis”. J Clin Gastroenterol 32 (3): 225–7.
  • Kupper C (2005). “Dietary guidelines and implementation for celiac disease”. Gastroenterology 128 (4 Suppl 1): S121–7.
  • Lundin K, Nilsen E, Scott H, Løberg E, Gjøen A, Bratlie J, Skar V, Mendez E, Løvik A, Kett K (2003). “Oats induced villous atrophy in coeliac disease“. Gut 52 (11): 1649–52.
  • Størsrud S, Olsson M, Arvidsson Lenner R, Nilsson L, Nilsson O, Kilander A (2003). “Adult coeliac patients do tolerate large amounts of oats“. Eur J Clin Nutr 57 (1): 163–9.
  • Canadian Celiac Association: Position Statement on Oats”.
  • Gallagher, Eimear (2009). Gluten-free Food Science and Technology. Published by John Wiley and Sons,. pp. 320.
  • Hopper A, Cross S, Hurlstone D, McAlindon M, Lobo A, Hadjivassiliou M, Sloan M, Dixon S, Sanders D (2007). “Pre-endoscopy serological testing for coeliac disease: evaluation of a clinical decision tool“. BMJ 334: 729.
  • Sblattero D, Berti I, Trevisiol C, et al (May 2000). “Human recombinant tissue transglutaminase ELISA: an innovative diagnostic assay for celiac disease“. Am. J. Gastroenterol. 95 (5): 1253–7.
  • Hill ID. “What are the sensitivity and specificity of serological tests for celiac disease? Do sensitivity and specificity vary in different populations?” In: NIH Consensus Development Conference on Celiac Disease. Bethesda, Md.: U.S. National Institutes of Health, 2004;27–31.
  • Wong R, Steele R, Reeves G, Wilson R, Pink A, Adelstein S (2003). “Antibody and genetic testing in coeliac disease”. Pathology 35 (4): 285–304.
  • Korponay-Szabó I, Dahlbom I, Laurila K, Koskinen S, Woolley N, Partanen J, Kovács J, Mäki M, Hansson T (2003). “Elevation of IgG antibodies against tissue transglutaminase as a diagnostic tool for coeliac disease in selective IgA deficiency“. Gut 52 (11): 1567–71. doi:10.1136/gut.52.11.1567.
  • Hadithi M, von Blomberg BM, Crusius JB, et al (2007). “Accuracy of serologic tests and HLA-DQ typing for diagnosing celiac disease“. Ann. Intern. Med. 147 (5): 294–302.
  • Niveloni S, Fiorini A, Dezi R, Pedreira S, Smecuol E, Vazquez H, Cabanne A, Boerr LA, Valero J, Kogan Z, Maurino E, Bai JC. (1998). “Usefulness of videoduodenoscopy and vital dye staining as indicators of mucosal atrophy of celiac disease: assessment of interobserver agreement”. Gastrointestinal Endoscopy 47 (3): 223–229. doi:10.1016/S0016-5107(98)70317-7.
  • Mee A, Burke M, Vallon A, Newman J, Cotton P (1985). “Small bowel biopsy for malabsorption: comparison of the diagnostic adequacy of endoscopic forceps and capsule biopsy specimens“. Br Med J (Clin Res Ed) 291 (6498): 769–72.
  • Marsh M (1992). “Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity (‘celiac sprue’)”. Gastroenterology 102 (1): 330–54.
  • Kim C, Quarsten H, Bergseng E, Khosla C, Sollid L (2004). “Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease“. Proc Natl Acad Sci USA 101 (12): 4175–9.
  • RD, Frau F, Cucca F, et al (2007). “HLA-DQB1*0201 homozygosis predisposes to severe intestinal damage in celiac disease”. Scand. J. Gastroenterol. 42 (1): 48–53.
  • Karell K, Louka AS, Moodie SJ, et al (2003). “HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease”. Hum. Immunol. 64 (4): 469–77.
  • Michalski J, McCombs C, Arai T, Elston R, Cao T, McCarthy C, Stevens F (1996). “HLA-DR, DQ genotypes of celiac disease patients and healthy subjects from the West of Ireland”. Tissue Antigens 47 (2): 127–33. PMID 8851726.
  • Kaur G, Sarkar N, Bhatnagar S, et al (2002). “Pediatric celiac disease in India is associated with multiple DR3-DQ2 haplotypes”. Hum. Immunol. 63 (8): 677–82.
  • Layrisse Z, Guedez Y, Domínguez E, Paz N, Montagnani S, Matos M, Herrera F, Ogando V, Balbas O, Rodríguez-Larralde A (2001). “Extended HLA haplotypes in a Carib Amerindian population: the Yucpa of the Perija Range”. Hum Immunol 62 (9): 992–1000.
  •  Green PH, Cellier C (October 2007). “Celiac disease”. N. Engl. J. Med. 357 (17): 1731–43.
  • Lammers KM, Lu R, Brownley J, et al (July 2008). “Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3″. Gastroenterology 135 (1): 194–204.e3.
  • Qiao SW, Bergseng E, Molberg Ø, et al (August 2004). “Antigen presentation to celiac lesion-derived T cells of a 33-mer gliadin peptide naturally formed by gastrointestinal digestion“. J. Immunol. 173 (3): 1757–62.
  • Shan L, Qiao SW, Arentz-Hansen H, et al (2005). “Identification and analysis of multivalent proteolytically resistant peptides from gluten: implications for celiac sprue“. J. Proteome Res. 4 (5): 1732–41.
  • Dieterich W, Ehnis T, Bauer M, Donner P, Volta U, Riecken E, Schuppan D (1997). “Identification of tissue transglutaminase as the autoantigen of celiac disease”. Nat Med 3 (7): 797–801.
  • Kaukinen K, Peraaho M, Collin P, Partanen J, Woolley N, Kaartinen T, Nuuntinen T, Halttunen T, Maki M, Korponay-Szabo I (2005). “Small-bowel mucosal tranglutaminase 2-specific IgA deposits in coeliac disease without villous atrophy: A Prospective and radmonized clinical study”. Scand J Gastroenterology 40: 564–572.
  • Salmi T, Collin P, Korponay-Szabó I, Laurila K, Partanen J, Huhtala H, Király R, Lorand L, Reunala T, Mäki M, Kaukinen K (2006). “Endomysial antibody-negative coeliac disease: clinical characteristics and intestinal autoantibody deposits“. Gut 55 (12): 1746–53.
  • Londei M, Ciacci C, Ricciardelli I, Vacca L, Quaratino S, and Maiuri L. (2005). “Gliadin as a stimulator of innate responses in celiac disease”. Mol Immunol 42 (8): 913–918.
  • Zanoni G, Navone R, Lunardi C, Tridente G, Bason C, Sivori S, Beri R, Dolcino M, Valletta E, Corrocher R, Puccetti A (2006). “In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes“. PLoS Med 3 (9): e358.
  • Salim A, Phillips A, Farthing M (1990). “Pathogenesis of gut virus infection”. Baillieres Clin Gastroenterol 4 (3): 593–607.
  • Stene L, Honeyman M, Hoffenberg E, Haas J, Sokol R, Emery L, Taki I, Norris J, Erlich H, Eisenbarth G, Rewers M (2006). “Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal study”. Am J Gastroenterol 101 (10): 2333–40.
  • Kagnoff M, Paterson Y, Kumar P, Kasarda D, Carbone F, Unsworth D, Austin R (1987). “Evidence for the role of a human intestinal adenovirus in the pathogenesis of coeliac disease” (PDF). Gut 28 (8): 995–1001.
  • Suman S, Williams E, Thomas P, Surgenor S, Snook J (2003). “Is the risk of adult coeliac disease causally related to cigarette exposure?”. Eur J Gastroenterol Hepatol 15 (9): 995–1000.
  • Norris JM, Barriga K, Hoffenberg EJ, Taki I, Miao D, Haas JE, Emery LM, Sokol RJ, Erlich HA, Eisenbarth GS, Rewers M. (2005). “Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease“. JAMA 293 (19): 2343–2351.

Artikel Seliak Lainnya

Pediatric Articles Dr Widodo Judarwanto (pediatrician)

100 Favorites Articles for Professional

.

supported by

PICKY EATERS AND GROW UP CLINIC (Klinik Khusus Kesulitan Makan dan Gangguan Berat Badan)  GRoW UP CLINIC JAKARTAYudhasmara Foundation  GRoW UP CLINIC I Jl Taman Bendungan Asahan 5 Bendungan Hilir Jakarta Pusat 10210, phone (021) 5703646 – 44466102 GRoW UP CLINIC II MENTENG SQUARE Jl Matraman 30 Jakarta Pusat 10430, phone (021) 44466103 – 97730777 email : judarwanto@gmail.com narulita_md@yahoo.com http://growupclinic.com

WORKING TOGETHER SUPPORT TO THE HEALTH OF ALL BY CLINICAL, RESEARCH AND EDUCATIONS. Advancing of the future pediatric and future parenting to optimalized physical, mental and social health and well being for fetal, newborn, infant, children, adolescents and young adult
“GRoW UP CLINIC” Jakarta Focus and Interest on: *** Allergy Clinic Online *** Picky Eaters and Growup Clinic For Children, Teen and Adult (Klinik Khusus Gangguan Sulit Makan dan Gangguan Kenaikkan Berat Badan)*** Children Foot Clinic *** Physical Medicine and Rehabilitation Clinic *** Oral Motor Disorders and Speech Clinic *** Children Sleep Clinic *** Pain Management Clinic Jakarta *** Autism Clinic *** Children Behaviour Clinic *** Motoric & Sensory Processing Disorders Clinic *** NICU – Premature Follow up Clinic *** Lactation and Breastfeeding Clinic *** Swimming Spa Baby & Medicine Massage Therapy For Baby, Children and Teen ***
Professional Healthcare Provider “GRoW UP CLINIC” Dr Narulita Dewi SpKFR, Physical Medicine & Rehabilitation curriculum vitae HP 085777227790 PIN BB 235CF967  Clinical – Editor in Chief : Dr Widodo Judarwanto, Pediatrician email : judarwanto@gmail.com Twitter: @WidoJudarwanto http://www.facebook.com/widodo.judarwanto Mobile Phone O8567805533 PIN BB 25AF7035

Curriculum Vitae Dr Widodo judarwanto, Pediatrician

We are guilty of many errors and many faults. But our worst crime is abandoning the children, neglecting the fountain of life.
Information on this web site is provided for informational purposes only and is not a substitute for professional medical advice. You should not use the information on this web site for diagnosing or treating a medical or health condition. You should carefully read all product packaging. If you have or suspect you have a medical problem, promptly contact your professional healthcare provider

Copyright © 2013, Picky Eaters and Grow Up Clinic, Information Education Network. All rights reserved

Tinggalkan Balasan

Isikan data di bawah atau klik salah satu ikon untuk log in:

Logo WordPress.com

You are commenting using your WordPress.com account. Logout / Ubah )

Gambar Twitter

You are commenting using your Twitter account. Logout / Ubah )

Foto Facebook

You are commenting using your Facebook account. Logout / Ubah )

Foto Google+

You are commenting using your Google+ account. Logout / Ubah )

Connecting to %s