Penyakit Alergi Atopi Dan IgG Anti Helicobacter Pylori

Asosiasi Antara Penyakit Alergi Atopi Dengan IgG Anti Helicobacter Pylori

Chairul Effendi,dr.,Sp.PD, K-AI

Abstact :
Background : Allergic disease is a disease based on the hypersensitivity reaction underlied by immunologic mechanism. Approximately 20% of the world population suffer from IgE-mediated allergic diseases. Although genetic factors play an important role in the manifestation of allergic disease, the existence of other factors such as lifestyle factors including environment, pollution, smoking, diet, socioeconomic factors and presence of infection, particularly orofecal infection including Helicobacter pylori infection also take a part. This is based on the hygiene hypothesis that infections in childhood can reduce allergies and autoimmune diseases.
Objective : To analyze negative association between atopic allergic diseases with anti-Hp IgG.

Material and method : This study is an observational analytic study with matched case control design, involving 52 patients consisting of 26 patients with atopic allergic diseases as a group of cases and 26 non-atopic patients as a control. Allergic disease was diagnosed by anamnesis, physical examination, and skin prick tests, whereas IgG anti Hp was measured using immunochromatography technique.

Result : Result from this study is that the prevalence of Helicobacter pylori infection based on serology in all samples is 76.92%, while the prevalence of Helicobacter pylori infection based on serology in the patients with allergy disease in particular is 73.08%. There is negative association between atopic allergic diseases with IgG anti Hp, meaning that the presence of IgG anti Hp is a protective factor of the occurrence of atopic allergic disease with OR=0.67 (95% CI 0.02 to 8.85).

Conclusion : There is negative association between atopic allergic diseases with IgG anti Hp, whereas IgG anti Hp is a protective factor of atopic allergic diseases.

Keyword : Alergi Atopi IgG Anti Helicobacter Pylori

supported by

CHILDREN GRoW UP CLINIC Yudhasmara Foundation Inspirasi Orangtua Cerdas, Tumbuhkan Anak Semakin Sehat, Kuat dan Pintar

WORKING TOGETHER FOR STRONGER, SMARTER AND HEALTHIER CHILDREN BY EDUCATION, CLINICAL INTERVENTION, RESEARCH AND NETWORKING INFORMATION . Advancing of the future pediatric and future parenting to optimalized physical, mental and social health and well being for fetal, newborn, infant, children, adolescents and young adult

LAYANAN KLINIK KHUSUS “CHILDREN GRoW UP CLINIC”

PROFESIONAL MEDIS “CHILDREN GRoW UP CLINIC”

  • Dr Narulita Dewi SpKFR, Physical Medicine & Rehabilitation
  • Dr Widodo Judarwanto SpA, Pediatrician
  • Fisioterapis

Clinical – Editor in Chief :

Dr WIDODO JUDARWANTO SpA, pediatrician

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