Autoimmune mechanism and relationship between multiple sclerosis and inflammatory bowel disease.

Autoimmun Rev. 2013 Oct 12. pii: S1568-9972(13)00175-4.

New insights into an autoimmune mechanism, pharmacological treatment and relationship between multiple sclerosis and inflammatory bowel disease.

Lin CH, Kadakia S, Frieri M.

Abstract

Inflammatory bowel disease (IBD) and multiple sclerosis (MS) are autoimmune diseases with a close relationship to their disease pattern and immunologic cascade with considerable morbidity and mortality. This article provides insight of why tumor necrosis factor blockers couldn’t work in multiple sclerosis and why interferon-beta doesn’t work in inflammatory bowel disease. In this article, we provide a detailed review of the linkage and potential interchangeable medication between IBD and MS in addition to Natalizumab, Trichuris suis egg therapy and vitamin D. Different treatment strategies may have potential in treating both diseases in the future.

Source: Department of Medicine, Department of Neurology and Division of Allergy Immunology, Nassau University Medical Center, East Meadow, NY, USA. Electronic

 

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Gejala Alergi pada bayi dan anak justru paling sering dipicu oleh adanya infeksi khususnya infeksi virus. Tetapi sebaliknya saat itu sering dianggap karena alergi susu atau alergi makanan. Gejala infeksi virus pada bayi khususnya sulit dikenali karena mirip gejala alergi. Reaksi terhadap alergi susu atau alergi makanan biasanya relatif ringan, namun begitu dipicu infeksi manifestasinya lebih berat. Pemicu alergi tidak akan berarti bila penyebab alergi dihindari. Widodo Judarwanto 2012
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